SID MEDICOS Studies Demonstrate LemonBottle Benefits for Cellulite Appearance, Hydration and Radiance

The LemonBottle product range. From left: Skin Booster, Ampoule Solution and REBOOT.

Clinical studies conducted on three products: Ampoule Solution, Skin Booster and REBOOT
Results demonstrate improvements in the appearance of cellulite, hydration, radiance, skin texture, elasticity and soothing
– Skin Booster and REBOOT classified as low irritation products in studies on normal and sensitive skin

Global beauty and aesthetics company SID MEDICOS has completed clinical studies on key products from its LemonBottle brand, objectively confirming their respective skin-improving effects benefits and low irritation potential, the company announced on 27 August.

The studies covered three LemonBottle products: Ampoule Solution, Skin Booster and REBOOT. Conducted by OATC Skin Clinical Trials Centre, a specialist skin testing institution, the studies assessed a range of benefits based on the characteristics of each product, including improvements in cellulite, skin hydration, radiance, tone, texture, elasticity and soothing.

Ampoule Solution demonstrated statistically significant improvements in key skin parameters related to cellulite after four weeks of use with an MTS roller. The study evaluated the thigh area of 33 women aged 20 to 50. Skin surface roughness, the length of the boundary between the dermis and subcutaneous fat layer, and cellulite grades based on expert visual assessment all decreased compared with baseline.

In a clinical study in which Skin Booster was used with an MTS roller, skin hydration increased by 45.44% and radiance by 17.78% after three days. Statistically significant improvements were observed across seven skin parameters, including improvements in skin brightness, density and elasticity, as well as reduced roughness and fine lines around the eyes.

REBOOT also demonstrated significant improvements when used with an MTS roller. After three days, skin hydration increased by 71.17% and radiance by 27.82%. Redness decreased by 7.51% and skin roughness by 9.24%, with statistically significant improvements confirmed across seven parameters, including skin brightness, density and elasticity.

The low irritation potential of Skin Booster and REBOOT were also evaluated. Skin patch tests were conducted on 30 adults with normal skin and 34 adults with sensitive skin. Both products recorded a skin irritation index of 0.00 and were classified as low irritation for both normal and sensitive skin.

A SID MEDICOS spokesperson said “These clinical studies are significant because they objectively demonstrate the skin-improving effects benefits of each LemonBottle product in line with its specific characteristics and intended use. We will continue to build scientific evidence through research, development and clinical studies, while expanding a product portfolio that global consumers and beauty professionals can trust.”

SID MEDICOS supplies its global beauty and aesthetics brand LemonBottle to more than 86 countries worldwide. The company received Korea’s US$20 Million Export Tower award in 2024 and continues to advance product research and development and expand its global presence under its vision, “Technology for Healthy Beauty.”

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□ About SID MEDICOS Co., Ltd.
Founded in 2020, SID MEDICOS is a global beauty and aesthetics company that develops face and body care products for markets worldwide. Led by its flagship brand LemonBottle, the company has established a presence in more than 86 countries and works with over 450 authorised partners globally.
In 2024, SID MEDICOS received the USD 20 Million Export Tower award at Korea’s 61st Trade Day and established a US subsidiary to strengthen its distribution and supply network across North America. Guided by its vision, “Technology for Healthy Beauty”, the company continues to strengthen its research and development, quality management, global distribution and product authenticity verification systems as it grows into a trusted global beauty brand.


□ About LemonBottle
LemonBottle is SID MEDICOS’ global professional aesthetics brand, available in more than 86 countries with over four million vials sold worldwide. Centred on Ampoule Solution for body contouring, the brand is expanding its professional skincare portfolio with Skin Booster for hydration, radiance and firmness care, and REBOOT, a three-step K-clinic programme.
LemonBottle aims to build an ecosystem encompassing education, product development, professional care programmes and aftercare in collaboration with aesthetics professionals worldwide. It also operates a unique serialised QR-code system for product authenticity verification and an authenticity certification mark scheme for authorised distributors and clinics. Further information is available at lemonbottle.net.

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